The Mack Lab
Gene expression is a molecular phenotype that is essential to organismal form and fitness. Understanding how gene regulation evolves over time and contributes to phenotypic differences within and between species is essential to understanding evolution. The overarching goals of our research program are to characterize the nature of regulatory variation as well as its role in evolutionary processes like adaptation and speciation.
Gene regulatory evolution and adaptation
Gene regulatory network evolution and speciation
New species form when reproductive isolation evolves between diverging populations. Critical to understanding the formation of new species is characterizing the genetic loci involved in post-zygotic reproductive isolation (e.g., hybrid sterility or inviability).
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Mack et al. 2019, Genes
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